Volume 6 Issue 1
Jun.  2022
Turn off MathJax
Article Contents
Shengwang Chen, Congjie Zhang. Perspectives on air disinfection methods in the workplace of blood transfusion services[J]. Blood&Genomics, 2022, 6(1): 21-26. doi: 10.46701/BG.2022012022005
Citation: Shengwang Chen, Congjie Zhang. Perspectives on air disinfection methods in the workplace of blood transfusion services[J]. Blood&Genomics, 2022, 6(1): 21-26. doi: 10.46701/BG.2022012022005

Perspectives on air disinfection methods in the workplace of blood transfusion services

doi: 10.46701/BG.2022012022005
More Information
  • Corresponding author: Shengwang Chen, Department of Quality Management, Hezhou Blood Center, Hezhou, Guangxi 542899, China. E-mail: 2807509171@qq.com
  • Received Date: 2022-03-31
  • Rev Recd Date: 2022-04-15
  • Accepted Date: 2022-04-26
  • Available Online: 2022-06-30
  • Publish Date: 2022-06-30
  • Blood collection and preparation is a relatively open operation in a conventional environment, and is vulnerable to be contaminated by various types of airborne pathogenic microorganisms. It is important to establish stable and effective air disinfection methods for all types of environments in blood transfusion services, in order to control air hygiene quality and thus reduce the probability of contamination during blood collection. This paper analyzes and summarizes the principles, advantages, and disadvantages of commonly used chemical and physical air disinfection methods and their application status. It is suggested that over-reliance on chemical reagents and disinfection facilities be reduced, so that better results can be achieved with the combination of multiple disinfection methods and dynamic air hygiene monitoring.


  • loading
  • [1]
    Eder AF, Dy BA, DeMerse B, et al. Apheresis technology correlates with bacterial contamination of platelets and reported septic transfusion reactions[J]. Transfusion, 2017, 57(12): 2969−2976. doi: 10.1111/trf.14308
    Chen XM, Gao LH, Huang MF, et al. Factors affecting the quality and countermeasures of sterilization in hospitals[J]. Chin J Nosocomiol (in Chinese), 2016, 26(7): 1658–1662.
    Li Z, Hou TW, Li ZQ, et al. Microbial contamination and control measures of blood and blood products[J]. Med Pharm J Chin People's Liberation Army (in Chinese), 2005, 17(1): 52–54.
    Wagner SJ, Robinette DE. Evaluation of swirling of swirling pH and glucose test for the detection of bacterial contamination in platelets concentrates[J]. Transfusion, 1996, 36: 989−1002. doi: 10.1046/j.1537-2995.1996.36111297091744.x
    Regulations for Technical Operation in Blood Banks, 2019 edition[S]. [2019-04-28]. http://www.nhc.gov.cn/yzygj/s7658/201905/bdd4f4ccd15c4201bfb6d9e7492d7fab.shtml
    Hygienic Standard for Disinfection in Hospitals: GB 15982-2012[S]. [2012-11-01]. http://openstd.samr.gov.cn/bzgk/gb/newGbInfo?hcno=4DA7977F7EFBF4B3181E3EE674DC82C8
    Zhou JY. Disinfection and infection management in blood banks[M]. 1st ed. Nanjing: Southeast University Press, 2018: 46.
    Wen SS, Zuo WC, Zhou Rui, et al. Research status and development trend of ultraviolet disinfection technology[J]. Opt Tech, 2020, 266(6): 26−32. doi: 10.13741/j.cnki.11-1879/o4.2020.06.006
    Dai CH, Wang YF, Wu ZF, et al. Accuracy measurement and traceability of UVC irradiance in ultraviolet disinfection[J]. Chin Illum Eng J (in Chinese), 2020, 31(2): 1–5.
    Li LL, Cao Q. Discussion on influencing factors and countermeasures of ultraviolet disinfection[J]. Chin J Pract Nurs, 2010, 20(10): 56−57.
    Wen XL, Li XM, Xin X, et al. Sterilization results and influencing factors for disinfection of wards using dynamic air disinfection machine[J]. J Nurs Sci (in Chinese), 2015, 30(24): 77–79.
    Lu WH, Xue FJ. Application of continuous quality improvement in the management of disinfection supply room[J]. Chin Med Herald (in Chinese), 2015, 12(17): 157–160.
    Zhao JJ, Ji H, Zhu M. Observation on efficacy of different air disinfection methods in blood-collecting environment[J]. Chin J Infect Control (in Chinese), 2007, 3(2): 115–116.
    Zhou M, Peng N, Dai Q, et al. Observation on disinfection effect of clinical common pathogens by high strength UV irradiation[J]. Chin J Disinfect (in Chinese), 2015, 32(3): 219–221.
    Xu Y, Tan Z, Sun J, et al. Study on efficacy of ozone air disinfector in killing microorganisms in air[J]. Chin J Disinfect (in Chinese), 2007, 24(1): 26–28.
    Qiu LJ, Li X, Zhang Y. Experimental observation on bactericidal efficacy of wall-hanging type ozone air disinfector[J]. Chin J Disinfect (in Chinese), 1997, 14(4): 228–229.
    Liu S, Fan PP. Research and application of ozone air disinfection machine in terminal disinfection of bed unit[J]. J Clin Med Lit (in Chinese), 2020, 7(10): 197–198.
    Li JR, Wang LN, Jin Y, et al. The research progress on air purification disinfection technology at home and abroad[J]. Environ Sci Technol (in Chinese), 2014, 37(S1): 204–209.
    Lu Q. Efficacy of ultraviolet ray, ozone disinfector, and circulating air disinfector in the air disinfection of outpatient blood collection room[J]. Chin J Infect Control (in Chinese), 2017, 16(3): 240–242.
    Hu XJ. EffIicacy of different air disinfection methods in blood collection environment[J]. Henan Med Res (in Chinese), 2016, 25(12): 2257–2258.
    Huang XY, Xu S, Jiang XC, et al. Experimental observation on air disinfection effect of ozone sterilizer[J]. Chin J Pub Health Eng (in Chinese), 2004, 3(1): 41–42.
    Wang W, Tan Z, Guo XL, et al. Comparison of the killing effects of two disinfection methods on bacterial spores on different media[J]. Chin J Disinfect (in Chinese), 2019, 36(12): 889–891.
    Ye MH, Ou SZ, Guo CN, et al. Observation on the disinfection efficacy of two air disinfection methods[J]. Chin J Nosoconmiol (in Chinese), 2001, 11(1): 45.
    Wang W, Guo XL, Chen WS, et al. Study on the bacillus subtilis spores killing effect of peroxyacetic acid fumigation on different medium and metal corrosion[J]. Chin J Disinfect (in Chinese), 2012, 29(12): 1088–1089.
    Tan JY, Yin SH, Zhang XX, et al. Effect of peracetic acid on disinfection of air in hospital[J]. Chin Health Stand Manage (in Chinese), 2017, 8(18): 129–130.
    Sun QH, Liu F, Zhang YX, et al. Disinfection efficacy of a hydrogen peroxide disinfection machine on the gynecologic outpatient operation room[J]. Chin J Disinfect (in Chinese), 2017, 34(9): 811–813, 816.
    Lin LW, Chen LY, Zhang CM, et al. The appropriate selection of disinfectants in the prevention and control of COVID-19[J]. Chin J Disinfect (in Chinese), 2020, 37(3): 226–229.
    Wu L, Luo J, Yang ZL, et al. Observation on the terminal disinfection effect of vaporized hydrogen peroxide on RICU wards[J]. Chin J Disinfect (in Chinese), 2019, 36(12): 902–904.
    Zhang SW, Yang JH, Chen YJ, et al. Terminal disinfection effect of hydrogen peroxide atomization sterilizer in blood centers[J]. Chin J Blood Transfus (in Chinese), 2021, 34(5): 532−535. doi: 10.13303/j.cjbt.issn.1004-549x.2021.05.023
    Liu LH, Song X, Wang L. Meta-analysis on disinfectant efficacy of air disinfector[J]. Chin J Infect Control (in Chinese), 2015, 14(7): 450–454.
    Shao SJ, Liu ZJ, Wang ZF, et al. Comparison on the air disinfection effect in blood store room between multi-functional air sterilizer and ultraviolet lamp[J]. Chin J Health Lab Technol (in Chinese), 2016, 26(3): 329–330, 334.
    Xie B. Analysis on the effect of ultraviolet circulating sterilizer for dynamic air disinfection in operating rooms[J]. Engineer Technol Res, 2020, 5(8): 243−244. doi: 10.19537/j.cnki.2096-2789.2020.08.117
    Yin Y, Zhang YW, Qian R. Observation on disinfection and sterilization effect of ultraviolet circulating air disinfector[C]. The 11th Academic Annual Meeting of Infection Management of Chinese Hospital Management Association, 2004: 374–375.
    Chou XP, Sun LQ, Liu XJ. Comparison of air disinfection efficacy of ultraviolet vehicle and circulating air disinfector in outpatient blood collection room[J]. Chin J Disinfect (in Chinese), 2014, 31(7): 785–786.
    Xu Y. Research progress of disinfection methods[J]. Jiangsu Health Care, 2001, 3(2): 7–8.
    Chen ZY, Lin LW, Li XN. Experimental study on the efficacy of the plasma air-sterilizing machine on air disinfection and purification[J]. Chin J Infect Control (in Chinese), 2007, 6(2): 112–114.
    Qiu YQ, Kang JB, Zhong ZX. Mechanism characteristics and maintenance of medical plasma air disinfector[J]. Chin J Med Device (in Chinese), 2013, 26(11): 70–71.
    Zheng W, Dai LY, Ke DG. Comparison of cleaning and disinfection effects of three kinds of air disinfectors in delivery room[J]. Prev Med, 2019, 31(7): 732−734. doi: 10.19485/j.cnki.issn2096-5087.2019.07.024
    Yu L, Li N, Jin AJ, et al. Evaluation on the bactericidal efficiency of a low temperature machine to microbiological aerosol[J]. Chin J Disinfect (in Chinese), 2017, 34(10): 902–904.
    D. Schieppati D, Galli F, Peyot ML. An ultrasound-assisted photocatalytic treatment to remove an herbicidal pollutant from waste waters[J]. Ultrason Sonochem, 2019, 54: 302−310. doi: 10.1016/j.ultsonch.2019.01.027
    Qian XL, Tang X, Tao CL. Treatment of exhaust emissions by negative pressure suction system in medical centers-photocatalyst purification box[J]. Med Gases Eng, 2018, 3(2): 24−27. doi: 10.19598/j.cnki.yyqtgc.2018.02.008
    Lin LN. Microstructure evolution and photocatalytic mechanism of TiO2-based photocatalyst[D]. Shanghai: East China Normal University, 2021.
    Xu SC, Dong K, Duo H, et al. Design and research of VOCs air purifier based on photocatalytic technology[J]. Mod Chem Ind, 2018, 38(6): 117−121. doi: 10.16606/j.cnki.issn0253-4320.2018.06.027
    Li BJ, Li BS, Wang L, et al. Evaluation of the sterilizing effect of an optimized photocatalytic air purifier with nano-sized TiO2 on staphylococcus albus[J]. Mod Prevent Med (in Chinese), 2014, 41(2): 359–361.
    Zhang YL, Ma L, Xue L, et al. Effect of nanometer light catalysis decontamination machine on air disinfection in hyperbaric oxygen chamber[J]. Chin J Nosocomiol (in Chinese), 2018, 18(8): 1118–1119.
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2543) PDF downloads(6) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint