Volume 1 Issue 1
Mar.  2017
Turn off MathJax
Article Contents
Wen Wu, Yecui Zhang, Xingying Guo, Peng Wu, Zhibo Zhang, Xiangyan Huang. Serological identification and molecular characterization of B (A) 02 subtype in patients and blood donors from Eastern China[J]. Blood&Genomics, 2017, 1(1): 55-59. doi: 10.46701/APJBG.20170117016
Citation: Wen Wu, Yecui Zhang, Xingying Guo, Peng Wu, Zhibo Zhang, Xiangyan Huang. Serological identification and molecular characterization of B (A) 02 subtype in patients and blood donors from Eastern China[J]. Blood&Genomics, 2017, 1(1): 55-59. doi: 10.46701/APJBG.20170117016

Serological identification and molecular characterization of B (A) 02 subtype in patients and blood donors from Eastern China

doi: 10.46701/APJBG.20170117016
  • Publish Date: 2017-03-30
  • This study was designed to identify the rare type ABO blood groups, B(A) 02, from Eastern China. Three samples with discordant serological results during routine blood type identification and four samples from one sample’ family were selected. All of them were detected by serological method. The exon 6 and 7 of the ABO genes were amplified by PCR and sequenced. They were typed as AsubB by serology and as BO by genotype. In AsubB samples, nt 700C>G mutation was detected in B gene, which was previously defined as B(A)02 alleles. In these seven samples, six showed B(A)02/O01 and one showed B(A)02/O02.B(A)02 allele was found to be more common in this study than B(A)04 which is considered to be more frequent than B(A)02. The careful identification of rare blood types is important for the safety of clinical blood transfusion.

     

  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1637) PDF downloads(1263) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return